Filtered By:
Condition: Cholesterol
This page shows you your search results in order of relevance.
Order by Relevance | Date
Total 42419 results found since Jan 2013.
Peripheral Neuropathy in Adolescents and Young Adults With Type 1 and Type 2 Diabetes From the SEARCH for Diabetes in Youth Follow-Up Cohort: A pilot study.
CONCLUSIONSDPN prevalence among youth with type 2 diabetes approached rates reported in adult populations with diabetes. Our findings suggest not only that youth with diabetes are at risk for DPN but also that many already show measurable signs of DPN.
PMID: 24144652 [PubMed - as supplied by publisher]
Source: Diabetes Care - October 21, 2013 Category: Endocrinology Authors: Jaiswal M, Lauer A, Martin CL, Bell RA, Divers J, Dabelea D, Pettitt DJ, Saydah S, Pihoker C, Standiford DA, Rodriguez BL, Pop-Busui R, Feldman EL, for The SEARCH For Diabetes In Youth Study Group Tags: Diabetes Care Source Type: research
The clinical characteristics and mutation search within monogenic diabetes genes in type 1 diabetes patients with long-term disease and preserved kidney function
CONCLUSIONS: Patients with long-term T1DM and well-preserved kidney function are characterized by good glycemic control, high HDL-cholesterol, low insulin requirements and near normal BMI. Monogenic diabetes mutations are not frequent among them.PMID:34825797 | DOI:10.20452/pamw.16143
Source: Molecular Medicine - November 26, 2021 Category: Molecular Biology Authors: Jerzy Hohendorff Magdalena Kwiatkowska Dorota Pisarczyk-Wiza Agnieszka Ludwig-S łomczyńska Magdalena Milcarek Przemys ław Kapusta Barbara Zapa ła Beata Kie ć-Wilk Iwona Trznadel-Morawska Magdalena Szopa Dorota Zozuli ńska-Ziółkiewicz Maciej T Ma Source Type: research
Prevalence of and Risk Factors for Diabetic Peripheral Neuropathy in Youth With Type 1 and Type 2 Diabetes: SEARCH for Diabetes in Youth Study
CONCLUSIONS
The high rates of DPN among youth with diabetes are a cause of concern and suggest a need for early screening and better risk factor management. Interventions in youth that address poor glycemic control and dyslipidemia may prevent or delay debilitating neuropathic complications.
Source: Diabetes Care - August 22, 2017 Category: Endocrinology Authors: Jaiswal, M.; Divers, J.; Dabelea, D.; Isom, S.; Bell, R. A.; Martin, C. L.; Pettitt, D. J.; Saydah, S.; Pihoker, C.; Standiford, D. A.; Dolan, L. M.; Marcovina, S.; Linder, B.; Liese, A. D.; Pop-Busui, R.; Feldman, E. L. Tags: Complications-Neuropathy Pathophysiology/Complications Source Type: research
Sugar-sweetened beverage intake and cardiovascular risk factor profile in youth with type 1 diabetes: application of measurement error methodology in the SEARCH Nutrition Ancillary Study.
Abstract
The SEARCH Nutrition Ancillary Study aims to investigate the role of dietary intake on the development of long-term complications of type 1 diabetes in youth, and capitalise on measurement error (ME) adjustment methodology. Using the National Cancer Institute (NCI) method for episodically consumed foods, we evaluated the relationship between sugar-sweetened beverage (SSB) intake and cardiovascular risk factor profile, with the application of ME adjustment methodology. The calibration sample included 166 youth with two FFQ and three 24 h dietary recall data within 1 month. The full sample included 2286 yo...
Source: The British Journal of Nutrition - July 16, 2015 Category: Nutrition Authors: Liese AD, Crandell JL, Tooze JA, Kipnis V, Bell R, Couch SC, Dabelea D, Crume TL, Mayer-Davis EJ Tags: Br J Nutr Source Type: research
Predictors of Dyslipidemia Over Time in Youth With Type 1 Diabetes: For the SEARCH for Diabetes in Youth Study
CONCLUSIONS
A1C and WHtR are modifiable risk factors associated with change in dyslipidemia over time in youth with type 1 diabetes.
Source: Diabetes Care - March 20, 2017 Category: Endocrinology Authors: Shah, A. S.; Maahs, D. M.; Stafford, J. M.; Dolan, L. M.; Lang, W.; Imperatore, G.; Bell, R. A.; Liese, A. D.; Reynolds, K.; Pihoker, C.; Marcovina, S.; DAgostino, R. B.; Dabelea, D. Tags: Cardiovascular and Metabolic Risk Source Type: research
Cardiovascular Risk Factors Are Associated With Increased Arterial Stiffness in Youth With Type 1 Diabetes: The SEARCH CVD study.
CONCLUSIONSPresence, clustering, and worsening of CV risk factors are associated with increased arterial stiffness over time in youth with type 1 diabetes. Whether improvement in CV risk factors early in life will slow the progression of arterial stiffness and reduce the burden of CV disease in this population requires further study.
PMID: 24101697 [PubMed - as supplied by publisher]
Source: Diabetes Care - October 7, 2013 Category: Endocrinology Authors: Dabelea D, Talton JW, D'Agostino R, Wadwa RP, Urbina EM, Dolan LM, Daniels SR, Marcovina SM, Hamman RF Tags: Diabetes Care Source Type: research
Postoperative statin use and risk of biochemical recurrence following radical prostatectomy: Results from the SEARCH database
ConclusionIn this retrospective cohort of men undergoing RP, postoperative statin use was significantly associated with reduced risk of BCR.Whether the association between postoperative statin use and BCR differs by race requires further study.Given these findings, coupled with other studies suggesting that statins may reduce risk of advanced PC, randomized controlled trials are warranted to formally test the hypothesis that statins slow PC progression.
Source: BJU International - March 3, 2014 Category: Urology & Nephrology Authors: Emma H. Allott, Lauren E. Howard, Matthew R. Cooperberg, Christopher J. Kane, William J. Aronson, Martha K. Terris, Christopher L. Amling, Stephen J. Freedland Tags: Urological Oncology Source Type: research
Longitudinal association between television watching and computer use and risk markers in diabetes in the SEARCH for Diabetes in Youth Study
ConclusionsYouth with T2D who increased their television watching over time vs. those who decreased it had larger increases in HbA1c over 5 yr. Youth with T1D who increased their television watching over time had increases in LDL‐c, TG, and to a lesser extent HbA1c.
Source: Pediatric Diabetes - June 1, 2014 Category: Endocrinology Authors: Chao Li, Bettina Beech, Tessa Crume, Ralph B D'Agostino, Dana Dabelea, Jill L Kaar, Angela D Liese, Elizabeth J Mayer‐Davis, Russell Pate, David J Pettitt, Craig Taplin, Beatriz Rodriguez, Anwar T Merchant Tags: Original Article Source Type: research
Search for the Most 'primitive' Membranes and Their Reinforcers: A Review of the Polyprenyl Phosphates Theory.
Abstract
Terpenoids have an essential function in present-day cellular membranes, either as membrane reinforcers in Eucarya and Bacteria or as principal membrane constituents in Archaea. We have shown that some terpenoids, such as cholesterol and α, ω-dipolar carotenoids reinforce lipid membranes by measuring the water permeability of unilamellar vesicles. It was possible to arrange the known membrane terpenoids in a 'phylogenetic' sequence, and a retrograde analysis led us to conceive that single-chain polyprenyl phosphates might have been 'primitive' membrane constituents. By using an optical microscopy, we ha...
Source: Origins of Life and Evolution of the Biosphere - October 30, 2014 Category: Molecular Biology Authors: Nakatani Y, Ribeiro N, Streiff S, Gotoh M, Pozzi G, Désaubry L, Milon A Tags: Orig Life Evol Biosph Source Type: research
UK DNA shared in worldwide search for genetic causes of disease
The genomes of thousands of Britons have been used to identify rare genetic varients that raise the risk of illnesses including heart disease and obesityThe DNA of thousands of British people has been read and made available to researchers around the world to boost the search for genetic causes of disease.The genomes of 4,000 healthy people are being shared with international scientists, along with detailed information on the participants’ height, weight, blood pressure, cholesterol levels and 60 other medical measurements. Continue reading...
Source: Guardian Unlimited Science - September 15, 2015 Category: Science Authors: Ian Sample Science editor Tags: Genetics Science Medical research Biology Source Type: news
In Search of an Optimal Target Level of Low Density Lipoprotein Cholesterol for Secondary Prevention Among the Japanese Population.
Authors: Morita H, Ishizaka N
PMID: 26830202 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - February 3, 2016 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research
Search for risk genes in Alzheimer's disease.
Abstract
Alzheimer's disease (AD) is the most common form of neurodegenerative dementia. The susceptibility to AD is determined by a complex interaction between genetic, epigenetic, and environmental factors. Herein, the risk that can be attributed to genetic factors is high (up to 80%). While most AD patients are sporadic, in rare families Mendelian mode of inheritance can be observed. In these rare familial cases, full penetrant mutations have been identified in APP, PSEN1, and PSEN2. Mutations in these three genes are however rarely found in sporadic AD. For over 20 years, the only known genetic risk factor i...
Source: Der Nervenarzt - June 2, 2017 Category: Neurology Authors: Karaca I, Wagner H, Ramirez A Tags: Nervenarzt Source Type: research
A genome-wide search for gene-by-obesity interaction loci of dyslipidemia in Koreans shows diverse genetic risk alleles Patient-Oriented and Epidemiological Research
Dyslipidemia is a well-established risk factor for CVD. Studies suggest that similar fat accumulation in a given population might result in different levels of dyslipidemia risk among individuals; for example, despite similar or leaner body composition compared with Caucasians, Asians of Korean descent experience a higher prevalence of dyslipidemia. These variations imply a possible role of gene-obesity interactions on lipid profiles. Genome-wide association studies have identified more than 500 loci regulating plasma lipids, but the interaction structure between genes and obesity traits remains unclear. We hypothesized th...
Source: The Journal of Lipid Research - December 1, 2019 Category: Lipidology Authors: Kang, M., Sung, J. Tags: Patient-Oriented and Epidemiological Research Source Type: research
Serum uric acid, predicts heart failure in a large Italian cohort: search for a cut-off value the URic acid Right for heArt Health study
Objective:
To assess the prognostic cut-off values of serum uric acid (SUA) in predicting fatal and morbid heart failure in a large Italian cohort in the frame of the Working Group on Uric Acid and Cardiovascular Risk of the Italian Society of Hypertension.
Methods:
The URic acid Right for heArt Health (URRAH) study is a nationwide, multicentre, cohort study involving data on individuals aged 18–95 years, recruited on a community basis from all regions of Italy under the patronage of the Italian Society of Hypertension with a mean follow-up period of 128 ± 65 months. Incident heart failure was defined on ...
Source: Journal of Hypertension - December 11, 2020 Category: Cardiology Tags: ORIGINAL PAPERS: Blood pressure and other risk factors Source Type: research
In search of the optimal setting for statin trials in prostate cancer: the power of population-based studies
Prostate Cancer and Prostatic Diseases, Published online: 29 March 2021; doi:10.1038/s41391-021-00355-yIn search of the optimal setting for statin trials in prostate cancer: the power of population-based studies
Source: Prostate Cancer and Prostatic Diseases - March 29, 2021 Category: Urology & Nephrology Authors: Emma H. Allott Emma L. Craig Konrad H. Stopsack Source Type: research
